Talking about Neurogastroenterology & Motility – our new format „ESNM inside“ gives insights into a somewhat underestimated discipline. Watch our first video with Professor Asbjørn Mohr Drewes from Aalborg University Hospital, Denmark. The video was instructed by Radislav Nanok, Bulgaria and Anne-Marie Wegeberg, Denmar
Differences in IBS Care and Training across Europe (DICE Study), supported by ESNM, aims to explore the variations in IBS training and management across Europe. We believe that this way, we will find the gaps in IBS education, which will help improve IBS management and will help improve education in this sector of Gastroenterology.
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Last year Prof. Jan Tack and Prof. Kok Ann Gwee jointly initiated a multicenter study entitled AEGIS (Asian European GastroIntestinal Symptoms). In 2018, both research groups have published contradictory results regarding symptom clusters in patients with a DGBI. Now, they started investigating where the differences in results come from.
Is it the difference in lifestyle in Eastern and Western countries?
Is it the difference in the questionnaire that was used in both studies (Rome IV and the Enhanced Asian Rome III questionnaire (EAR3Q))?
The current AEGIS protocol aims to compare an Eastern and Western DGBI cohorts that fill out both questionnaires to see what is necessary to develop a worldwide up to date classification system, considering both the Asian and the current Rome approach. Additional participating Eastern and Western research centers have been recruited and both professors are very enthusiastic about recruiting more.
The Principal Investigators that have currently showed interest: Prof. Jinsong Liu, Prof. Gerald Holtmann, Prof. Hidekazu Suzuki, and Prof. Sanjiv Mahadeva. Previous publications: https://doi.org/10.1016/j.cgh.2018.02.042 and https://doi.org/10.1016/j.cgh.2018.09.027
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A heritable component of functional dyspepsia (FD) has been demonstrated in cohorts of patients and community-based studies. However, genetic studies of FD have thus far been very scarce and mostly limited to candidate genes in small sample sets of cases and controls, hence no unequivocal FD risk locus has been proposed. Opposite to most human complex diseases, powered large-scale gene-hunting efforts and hypothesis-free genome-wide association studies (GWAS) have been completely lacking in FD, which represents some sort of “neglected disorder” in terms of genetic research.
The current FunDysGWAS proposal aims to study the genotype of fully characterized FD patients in different European countries. This study could contribute to key insight into the genetic predisposition of functional dyspepsia. This will also allow later in depth analyses of the potential effect of FD risk genes on associated intermediate phenotypes (endophenotypes) key to symptom generation.
Are you interested in participating as a recruiting research center? Contact us. More information: click here
In these newsletters, the editors will highlight exciting current and upcoming articles in Neurogastroenterology and Motility and celebrate the past successes. The Editor’s Choice articles are free downloads for one month. You are encouraged to give feedback and suggestions, as they continually strive to grow and improve the journal.
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We have reached a meaningful milestone by completing the first phase of the study with more than two-thousands patients enrolled from 36 Institutions. The drafting of the manuscript of the first study-phase is ongoing and we hope to send the first version of the paper by the end of the year.
The results of our case-control study would be widely useful to understand the impact of SARS-CoV-2 infection on gastrointestinal symptoms.
All physical persons holding or training for a PhD or MD who are interested in gastrointestinal motility and neurophysiology of the gut are eligible as members to ESNM.
The Gut Microbiota & Health is an initiative of the ESNM to reasearch the booming area of Gut Microbiota, and their role on human health.
The European Society of Neurogastroenterology and Motility ESNM is composed of a Steering Committee and a General Assembly.
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