Graphic Abstract: Esophageal Manometry

Graphic Abstract: The added value of symptom analysis during a rapid drink challenge in high-resolution esophageal manometry

One-line-comment: A significant proportion of patients with esophageal symptoms have a normal HRM or an inconclusive diagnosis performing the standard protocol. Provocative tests like RDC mimic normal eating conditions. Evaluating both symptoms and pressive patterns in RDC increases the specificity of esophageal motor testing and helps to discriminate between patients with symptoms associated with esophageal dysmotility or EGJ obstruction from patients with functional dysphagia.

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