A New International Questionnaire Study

A New International Questionnaire Study: What is Needed to Develop a Global Classification System for Disorders of the Gut-Brain Axis (DGBI)?

Last year Prof. Jan Tack and Prof. Kok Ann Gwee jointly initiated a multicenter study entitled AEGIS (Asian European GastroIntestinal Symptoms). In 2018, both research groups have published contradictory results regarding symptom clusters in patients with a DGBI. Now, they started investigating where the differences in results come from.

Is it the difference in lifestyle in Eastern and Western countries?

Is it the difference in the questionnaire that was used in both studies (Rome IV and the Enhanced Asian Rome III questionnaire (EAR3Q))?

The current AEGIS protocol aims to compare an Eastern and Western DGBI cohorts that fill out both questionnaires to see what is necessary to develop a worldwide up to date classification system, considering both the Asian and the current Rome approach. Additional participating Eastern and Western research centers have been recruited and both professors are very enthusiastic about recruiting more.

The Principal Investigators that have currently showed interest: Prof. Jinsong Liu, Prof. Gerald Holtmann, Prof. Hidekazu Suzuki, and Prof. Sanjiv Mahadeva. Previous publications: https://doi.org/10.1016/j.cgh.2018.02.042 and https://doi.org/10.1016/j.cgh.2018.09.027
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